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Assay Detail

CHEMBL5332035

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of H-Ras (unknown origin)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

GTPase HRas (CHEMBL2167)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

A decade of approved first-in-class small molecule orphan drugs: Achievements, challenges and perspectives.
Gu J, Wu Q, Zhang Q, You Q, Wang L.
Eur J Med Chem (2022) 243 : 114742 -114742
PubMed 36155354 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 8.72 8.72

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL66699 1 8.72

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL66699 IC50 = 1.9 nM 8.72