Assay Detail
Functional
CHEMBL5332212
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Antiproliferative activity against human HL-60 cells assessed as inhibition of cell growth
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HL-60 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Bisindole natural products: A vital source for the development of new anticancer drugs.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.32 | 6.77 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL506768 | CONOPHYLLINE | — | 1 | 6.77 |
| CHEMBL5398385 | — | — | 1 | 6.77 |
| CHEMBL5406271 | — | — | 1 | 5.42 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL506768 | CONOPHYLLINE | IC50 | = | 170.0 | nM | 6.77 |
| CHEMBL5398385 | — | IC50 | = | 170.0 | nM | 6.77 |
| CHEMBL5406271 | — | IC50 | = | 3800.0 | nM | 5.42 |