Assay Detail
Binding
CHEMBL5332372
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Inhibition of beta-Catenin/TCF4 (unknown origin) protein-protein interaction assessed as inhibition constant
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 7 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Recent advances of β-catenin small molecule inhibitors for cancer therapy: Current development and future perspectives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 4.18 | 4.27 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3589010 | — | — | 1 | 4.27 |
| CHEMBL3914848 | — | — | 1 | 4.09 |
| CHEMBL254381 | — | — | 1 | - |
| CHEMBL3589009 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3589010 | — | Ki | = | 53510.0 | nM | 4.27 |
| CHEMBL3914848 | — | Ki | = | 80340.0 | nM | 4.09 |
| CHEMBL254381 | — | Ki | = | 180990.0 | nM | - |
| CHEMBL3589009 | — | Ki | = | 364710.0 | nM | - |