Assay Detail
Binding
CHEMBL5333630
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Inhibition of telomerase (unknown origin)
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Telomerase: A prominent oncological target for development of chemotherapeutic agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 5.73 | 6.48 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL158083 | — | — | 1 | 6.48 |
| CHEMBL5396635 | — | — | 1 | 6.30 |
| CHEMBL2170855 | — | — | 1 | 6.19 |
| CHEMBL2170856 | — | — | 1 | 6.00 |
| CHEMBL5418047 | — | — | 1 | 4.92 |
| CHEMBL5408379 | — | — | 1 | 4.48 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL158083 | — | IC50 | = | 330.0 | nM | 6.48 |
| CHEMBL5396635 | — | IC50 | = | 500.0 | nM | 6.30 |
| CHEMBL2170855 | — | IC50 | = | 650.0 | nM | 6.19 |
| CHEMBL2170856 | — | IC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL5418047 | — | IC50 | = | 12000.0 | nM | 4.92 |
| CHEMBL5408379 | — | IC50 | = | 33000.0 | nM | 4.48 |