Assay Detail
Functional
CHEMBL5333942
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antimycobacterial activity against Mycobacterium smegmatis assessed as inhibition of mycobacterial growth incubated for 48 hrs in presence of 50 uM Upp
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mycolicibacterium smegmatis |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Target
Mycolicibacterium smegmatis (CHEMBL613088) ↗| Type | ORGANISM |
| Organism | Mycolicibacterium smegmatis |
Publication
Investigation into the Mechanism of Action of the Tuberculosis Drug Candidate SQ109 and Its Metabolites and Analogues in Mycobacteria.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.35 | 5.85 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL561057 | SQ109 | 2.0 | 1 | 5.85 |
| CHEMBL5412119 | — | — | 1 | 4.85 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL561057 | SQ109 | IC50 | = | 1400.0 | nM | 5.85 |
| CHEMBL5412119 | — | IC50 | = | 14000.0 | nM | 4.85 |