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Assay Detail

CHEMBL5336067

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Toxicity
Cytotoxicity against human SH-SY5Y cells incubated for 24 hrs by MTT assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Toxicity
Organism Homo sapiens
Cell Type SH-SY5Y
Confidence 1 — Organism
Curated By Autocuration

Target

SH-SY5Y (CHEMBL614910)
Type CELL-LINE
Organism Homo sapiens

Publication

Thioxanthenone-based derivatives as multitarget therapeutic leads for Alzheimer's disease.
Tonelli M, Catto M, Sabaté R, Francesconi V, Laurini E, Pricl S, Pisani L, Miniero DV, Liuzzi GM, Gatta E, Relini A, Gavín R, Del Rio JA, Sparatore F, Carotti A.
Eur J Med Chem (2023) 250 : 115169 -115169
PubMed 36753881 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.14 5.14

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5286183 1 5.14

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5286183 IC50 = 7220.0 nM 5.14