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Assay Detail

CHEMBL5336350

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of N-terminal His6-tagged SARS-CoV-2 Main protease
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Severe acute respiratory syndrome coronavirus 2
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Replicase polyprotein 1ab (CHEMBL4523582)
Type SINGLE PROTEIN
Organism Severe acute respiratory syndrome coronavirus 2

Publication

The research progress of SARS-CoV-2 main protease inhibitors from 2020 to 2022.
Pang X, Xu W, Liu Y, Li H, Chen L.
Eur J Med Chem (2023) 257 : 115491 -115491
PubMed 37244162 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.02 7.02

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5206756 1 7.02

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5206756 IC50 = 96.0 nM 7.02