Assay Detail
Functional
CHEMBL5336364
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against HCoV-229E infected in human Huh-7 cells assessed as reduction in viral replication
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Human coronavirus 229E |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
The research progress of SARS-CoV-2 main protease inhibitors from 2020 to 2022.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.76 | 7.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5182995 | — | — | 1 | 7.89 |
| CHEMBL5185801 | — | — | 1 | 7.62 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5182995 | — | IC50 | = | 13.0 | nM | 7.89 |
| CHEMBL5185801 | — | IC50 | = | 24.0 | nM | 7.62 |