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Assay Detail

CHEMBL5337669

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of SARS-CoV-2 main protease
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Severe acute respiratory syndrome coronavirus 2
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Replicase polyprotein 1ab (CHEMBL4523582)
Type SINGLE PROTEIN
Organism Severe acute respiratory syndrome coronavirus 2

Publication

Antiviral Protein-Protein Interaction Inhibitors.
Marković V, Szczepańska A, Berlicki Ł.
J Med Chem (2024) 67 : 3205 -3231
PubMed 38394369 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.26 7.26

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5398458 1 7.26

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5398458 IC50 = 55.0 nM 7.26