Assay Detail
Binding
CHEMBL5337709
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Agonist activity at ER-alpha (unknown origin) by ER-alpha coactivator assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Synthesis, biological evaluation, and stability studies of raloxifene mono- and bis-sulfamates as dual-targeting agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 8.73 | 8.85 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1405 | ESTRONE | 4.0 | 1 | 8.85 |
| CHEMBL411 | DIETHYLSTILBESTROL | 4.0 | 1 | 8.60 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1405 | ESTRONE | EC50 | = | 1.4 | nM | 8.85 |
| CHEMBL411 | DIETHYLSTILBESTROL | EC50 | = | 2.5 | nM | 8.60 |