Assay Detail
Binding
CHEMBL5337969
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of C-terminal NanoLuc-tagged MPGLWKS peptide from N-terminal HaloTag-tagged GID4 (unknown origin) expressed in HEK293T cells incubated for 4 hrs by fluorescence polarization based NanoBRET assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | HEK293T |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Glucose-induced degradation protein 4 homolog (CHEMBL5169174) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Chemical tools for the Gid4 subunit of the human E3 ligase C-terminal to LisH (CTLH) degradation complex.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 5.60 | 5.60 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5411984 | — | — | 1 | 5.60 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5411984 | — | IC50 | = | 2500.0 | nM | 5.60 |