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Assay Detail

CHEMBL5340258

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to BRD4 (unknown origin)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Bromodomain-containing protein 4 (CHEMBL1163125)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Modulation of ERK5 Activity as a Therapeutic Anti-Cancer Strategy.
Miller DC, Harnor SJ, Martin MP, Noble RA, Wedge SR, Cano C.
J Med Chem (2023) 66 : 4491 -4502
PubMed 37002872 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 1 5.44 5.44

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4541479 1 5.44

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4541479 Kd = 3600.0 nM 5.44