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Assay Detail

CHEMBL5340519

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to G-quadruplex DNA c-kit1 (unknown origin) by fluorescence spectroscopic analysis
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Not specified
Confidence 3 — Cell-line / Tissue
Curated By Autocuration

Target

quadruplex DNA (CHEMBL3832742)
Type NUCLEIC-ACID
Organism Homo sapiens

Publication

Development and Characterization of Benzoselenazole Derivatives as Potent and Selective <i>c-MYC</i> Transcription Inhibitors.
Wu TY, Chen XC, Tang GX, Shao W, Li ZC, Chen SB, Huang ZS, Tan JH.
J Med Chem (2023) 66 : 5484 -5499
PubMed 37036951 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 2 5.11 5.19

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5433462 1 5.19
CHEMBL5428440 1 5.02

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5433462 Kd = 6500.0 nM 5.19
CHEMBL5428440 Kd = 9600.0 nM 5.02