Assay Detail
Binding
CHEMBL5340576
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Binding affinity to FXIa (unknown origin) assessed as inhibition constant
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Factor XIa Inhibitors in Anticoagulation Therapy: Recent Advances and Perspectives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 9.29 | 9.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4112929 | MILVEXIAN | 3.0 | 1 | 9.96 |
| CHEMBL5413065 | — | — | 1 | 9.60 |
| CHEMBL5416393 | — | — | 1 | 8.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4112929 | MILVEXIAN | Ki | = | 0.11 | nM | 9.96 |
| CHEMBL5413065 | — | Ki | = | 0.25 | nM | 9.60 |
| CHEMBL5416393 | — | Ki | = | 5.0 | nM | 8.30 |