Assay Detail
Binding
CHEMBL5342193
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antagonist activity at TLR4 in mouse peritoneal macrophages assessed as inhibition of IL-6 production
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mus musculus |
| Cell Type | Peritoneal macrophage |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Small-Molecule Modulators Targeting Toll-like Receptors for Potential Anticancer Therapeutics.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 8.89 | 8.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL225157 | RESATORVID | 3.0 | 1 | 8.89 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL225157 | RESATORVID | IC50 | = | 1.3 | nM | 8.89 |