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Assay Detail

CHEMBL5342199

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to TLR1/TLR2 (unknown origin) assessed as inhibition constant
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 7 — Homologous single protein target
Curated By Autocuration

Target

Toll-like receptor 1/2 (CHEMBL3885643)
Type PROTEIN COMPLEX
Organism Homo sapiens

Publication

Small-Molecule Modulators Targeting Toll-like Receptors for Potential Anticancer Therapeutics.
Wang J, Zhang J, Wang J, Hu X, Ouyang L, Wang Y.
J Med Chem (2023) 66 : 6437 -6462
PubMed 37163340 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 6.39 6.39

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3935646 1 6.39

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3935646 Ki = 410.0 nM 6.39