Assay Detail
Binding
CHEMBL5342202
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Antagonist activity at TLR1/TLR2 in HEK-Blue hTLR2 cells
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | HEK-Blue hTLR2 |
| Confidence | 7 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Small-Molecule Modulators Targeting Toll-like Receptors for Potential Anticancer Therapeutics.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.67 | 4.71 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4227186 | — | — | 1 | 4.71 |
| CHEMBL13859 | — | — | 1 | 4.62 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4227186 | — | IC50 | = | 19700.0 | nM | 4.71 |
| CHEMBL13859 | — | IC50 | = | 24200.0 | nM | 4.62 |