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Assay Detail

CHEMBL5345106

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Anticancer activity against human TC-32 cells assessed as reduction in cell growth incubated for 48 hrs by SRB assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type TC-32
Confidence 1 — Organism
Curated By Autocuration

Target

TC-32 (CHEMBL4296499)
Type CELL-LINE
Organism Homo sapiens

Publication

Phenothiazines as anti-cancer agents: SAR overview and synthetic strategies.
Kumar A, Vigato C, Boschi D, Lolli ML, Kumar D.
Eur J Med Chem (2023) 254 : 115337 -115337
PubMed 37060756 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 3 5.81 6.27

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5403230 1 6.27
CHEMBL5394819 1 5.82
CHEMBL5419608 1 5.34

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5403230 IC50 = 540.0 nM 6.27
CHEMBL5394819 IC50 = 1530.0 nM 5.82
CHEMBL5419608 IC50 = 4570.0 nM 5.34