Assay Detail
Binding
CHEMBL5345246
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Haemophilus influenzae DapE at 80 degreeC incubated for 15 mins by ninhydrin based assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Haemophilus influenzae |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Succinyl-diaminopimelate desuccinylase (CHEMBL1075192) ↗| Type | SINGLE PROTEIN |
| Organism | Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) |
Publication
Synthesis and characterization of the N-succinyl-l,l-diaminopimelic acid desuccinylase (DapE) alternate substrate analog N,N-dimethyl-l,l-SDAP.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 6.05 | 6.05 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5425782 | — | — | 1 | 6.05 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5425782 | — | IC50 | = | 890.0 | nM | 6.05 |