Assay Detail
Binding
CHEMBL5346622
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Binding affinity to dopamine D1 receptor (unknown origin) assessed as inhibition constant
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Indole-containing pharmaceuticals: targets, pharmacological activities, and SAR studies.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 9.16 | 9.47 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL157138 | LISURIDE | 3.0 | 1 | 9.47 |
| CHEMBL1201087 | CABERGOLINE | 4.0 | 1 | 8.85 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL157138 | LISURIDE | Ki | = | 0.34 | nM | 9.47 |
| CHEMBL1201087 | CABERGOLINE | Ki | = | 1.4 | nM | 8.85 |