Assay Detail
Binding
CHEMBL5346707
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Inhibition of 5-HT2BR (unknown origin ) assessed as inhibition constant
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Synthesis and bioactivity of psilocybin analogues containing a stable carbon-phosphorus bond.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 7.68 | 8.34 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL65547 | PSILOCIN | 2.0 | 1 | 8.34 |
| CHEMBL194378 | PSILOCYBIN | 3.0 | 1 | 7.01 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL65547 | PSILOCIN | Ki | = | 4.6 | nM | 8.34 |
| CHEMBL194378 | PSILOCYBIN | Ki | = | 98.7 | nM | 7.01 |