Assay Detail

CHEMBL5347332

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Functional

Antiviral activity against human enterovirus 71

ChEMBL ↗

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Target

Enterovirus A71 (CHEMBL612436) ↗

Open DB target context

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Enterovirus A71 (CHEMBL612436) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target Enterovirus A71

CHEMBL612436

Anchored from Assay target.

Protein identity Enterovirus A71

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Enterovirus A71
Confidence	1 — Organism
Curated By	Autocuration

Target

Enterovirus A71 (CHEMBL612436) ↗

Type	ORGANISM
Organism	Enterovirus A71

Publication

Rational design of novel nucleoside analogues reveals potent antiviral agents for EV71.

Salerno M, Varricchio C, Bevilacqua F, Jochmans D, Neyts J, Brancale A, Ferla S, Bassetto M.
Eur J Med Chem (2023) 246 : 114942 -114942
PubMed 36455356 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
EC50	1	6.55	6.55

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL388757	N6-BENZYLADENOSINE	—	1	6.55

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL388757	N6-BENZYLADENOSINE	EC50	=	280.0	nM	6.55