Assay Detail
Binding
CHEMBL5348349
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of EED (unknown origin)
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Triazole-fused pyrimidines in target-based anticancer drug discovery.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 7.13 | 8.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4755618 | — | — | 1 | 8.30 |
| CHEMBL4065484 | — | — | 1 | 7.52 |
| CHEMBL4759335 | — | — | 1 | 7.30 |
| CHEMBL4096234 | — | — | 1 | 5.39 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4755618 | — | IC50 | = | 5.0 | nM | 8.30 |
| CHEMBL4065484 | — | IC50 | = | 30.0 | nM | 7.52 |
| CHEMBL4759335 | — | IC50 | = | 50.0 | nM | 7.30 |
| CHEMBL4096234 | — | IC50 | = | 4030.0 | nM | 5.39 |