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Assay Detail

CHEMBL5349945

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Functional
Antiviral activity against cidofovir-resistant Vaccinia virus infected in African monkey Vero cells measured after 5 days by MTT assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Vaccinia virus
Cell Type Vero
Confidence 1 — Organism
Curated By Autocuration

Target

Vaccinia virus (CHEMBL613493)
Type ORGANISM
Organism Vaccinia virus

Publication

An Overview of Antivirals against Monkeypox Virus and Other Orthopoxviruses.
Wang J, Shahed-Ai-Mahmud M, Chen A, Li K, Tan H, Joyce R.
J Med Chem (2023) 66 : 4468 -4490
PubMed 36961984 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.40 7.40

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1631219 1 7.40

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1631219 IC50 = 40.0 nM 7.40