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Target Snapshot

CHEMBL613493 Target Snapshot

Vaccinia virus · ORGANISM · Vaccinia virus

Back to Search Search this target Browse approvals Evidence Card
3,527Compounds
495Assays
27Approved Drugs
2,118.0Activities
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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

Confirm a stable target identifier before relying on this context across project surfaces.

Review focus
Open DB context pending

Confirm a stable target identifier before relying on this context across project surfaces.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Vaccinia virus as ChEMBL target CHEMBL613493. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Vaccinia virus
ORGANISM · Vaccinia virus
As of 2026-09-14
ChEMBL target ID
CHEMBL613493
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

Choose the first block or source based on the question you are trying to answer.

Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Vaccinia virus still has a stable protein naming contract across sources.

Jump to Protein Context
Need disease fit before discussing compounds?
Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

Preferred NameVaccinia virus
Target TypeORGANISM
OrganismVaccinia virus
ChEMBL ↗ NCBI Taxonomy ↗

Next Actions

SearchRun a focused querySearch the database using this target name as the starting context. ApprovalsCheck approved moleculesSee which approved drugs connect back to this target and its surrounding signal space. FeedScan papers & updatesStay in the project thread while checking recent papers and platform updates.
UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelVaccinia virus
UniProt AccessionN/A

Vaccinia virus

Source · UniProt accession via ChEMBL component mapping
UniProt Context ↗
Review Cue

How to read this target

Review this target as Vaccinia virus.

Review nameVaccinia virus
OrganismVaccinia virus
Clinical Profile

Clinical Phase Distribution

27
Approved
4
Phase III
10
Phase II
2
Phase I
Assay Mix

Activity Type Distribution

IC50505.0
EC501,613.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL504793 9.74 IC50 0.18 Preclinical
CHEMBL147814 9.15 IC50 0.7 Preclinical
CHEMBL1255998 9.13 EC50 0.74 Preclinical
CHEMBL1258896 9.13 EC50 0.74 Preclinical
CHEMBL342983 9.07 IC50 0.86 Preclinical
CHEMBL1258440 8.92 EC50 1.2 Preclinical
CHEMBL146182 8.92 IC50 1.2 Preclinical
CHEMBL146197 8.92 IC50 1.2 Preclinical
CHEMBL146699 8.92 IC50 1.2 Preclinical
CHEMBL148304 8.92 IC50 1.2 Preclinical
Distribution

pChEMBL Value Distribution

178
5.0
121
5.5
81
6.0
46
6.5
39
7.0
14
7.5
13
8.0
18
8.5
4
9.0
1
9.5
pChEMBL
Approved Drugs

Approved Drugs

BRINCIDOFOVIR
CHEMBL203321
Approved 2021
Properties Compare Identifier
TECOVIRIMAT
CHEMBL1257073
Approved 2018
Properties Compare Identifier
MYCOPHENOLIC ACID
CHEMBL866
Approved 2004
Properties Compare Identifier
MYCOPHENOLATE MOFETIL
CHEMBL1456
Approved 1995
Properties Compare Identifier
MITOXANTRONE
CHEMBL58
Approved 1987
Properties Compare Identifier
ACYCLOVIR
CHEMBL184
Approved 1982
Properties Compare Identifier
VIDARABINE
CHEMBL1090
Approved 1976
Properties Compare Identifier
DIGOXIN
CHEMBL1751
Approved 1975
Properties Compare Identifier
IDOXURIDINE
CHEMBL788
Approved 1963
Properties Compare Identifier
EMETINE
CHEMBL50588
Properties Compare Identifier
Assay Landscape

Assay Landscape

495
Total Assays
630
Tested Compounds
2
Assay Types
Functional — 493 assays, 630 compounds
BAO Format Assays Compounds Avg pChEMBL
organism-based format 480 620 5.4
assay format 8 4 4.9
cell-based format 5 6 4.7
ADME — 2 assays, 0 compounds
BAO Format Assays Compounds Avg pChEMBL
organism-based format 2 0 —

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine