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Assay Detail

CHEMBL5349971

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiviral activity against Herpes simplex virus 2
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Human alphaherpesvirus 2
Confidence 1 — Organism
Curated By Autocuration

Target

Human alphaherpesvirus 2 (CHEMBL370)
Type ORGANISM
Organism Human alphaherpesvirus 2

Publication

An Overview of Antivirals against Monkeypox Virus and Other Orthopoxviruses.
Wang J, Shahed-Ai-Mahmud M, Chen A, Li K, Tan H, Joyce R.
J Med Chem (2023) 66 : 4468 -4490
PubMed 36961984 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 5.04 5.62

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL473535 FENTICLOR 2.0 1 5.62
CHEMBL1898204 1 4.46

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL473535 FENTICLOR IC50 = 2400.0 nM 5.62
CHEMBL1898204 IC50 = 34800.0 nM 4.46