Compound Detail
CHEMBL473535
FENTICLOR 🧪 Phase II
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
🧪 Phase II
Basic Information
| ChEMBL ID | CHEMBL473535 |
| Name | FENTICLOR |
| Phase | Phase II |
| Structure Type | MOL |
| InChI Key | ANUSOIHIIPAHJV-UHFFFAOYSA-N |
7
Targets
19
Activities
2
Assay Types
0
PK Parameters
10
Publications
7
Known Names
Molecular Properties
287.2
MW (Da)
4.56
ALogP
3
HBA
2
HBD
40.5
PSA (Ų)
0.85
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Chirality | Achiral |
Activity Summary
IC50 18 meas. best 7.12
EC50 1 meas. best 4.73
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | IC50 | 7.12 | 6.0727 | 75.0 | 11 |
| Human alphaherpesvirus 2 CHEMBL370 | IC50 | 5.62 | 5.62 | 2400.0 | 1 |
| Vaccinia virus CHEMBL613493 | IC50 | 5.24 | 5.24 | 5700.0 | 1 |
| Cysteine protease ATG4B CHEMBL1741221 | IC50 | 4.96 | 4.96 | 11000.0 | 1 |
| Phospholipase A2 CHEMBL4426 | IC50 | 4.82 | 4.82 | 15200.0 | 1 |
| Vaccinia virus CHEMBL613493 | EC50 | 4.73 | 4.73 | 18700.0 | 1 |
| Plasmodium falciparum CHEMBL364 | IC50 | 4.69 | 4.68 | 20500.0 | 2 |
| Uracil-DNA glycosylase CHEMBL1772931 | IC50 | 4.42 | 4.42 | 38500.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 36256884 | 10.1021/acs.jmedchem.2c01437 | Staphylococcus aureus | 3 |
| 19191586 | 10.1021/jm8008103 | Plasmodium falciparum | 2 |
| - | 10.6019/CHEMBL4651402 | SARS-CoV-2 | 2 |
| 19191586 | 10.1021/jm8008103 | Unchecked | 1 |
| 21438571 | 10.1021/jm101554k | Uracil-DNA glycosylase | 1 |
| 21438571 | 10.1021/jm101554k | Vaccinia virus | 1 |
| 21438571 | 10.1021/jm101554k | BSC-1 | 1 |
| 36256884 | 10.1021/acs.jmedchem.2c01437 | Erythrocyte | 1 |
| 36961984 | 10.1021/acs.jmedchem.3c00069 | Vaccinia virus | 1 |
| 36961984 | 10.1021/acs.jmedchem.3c00069 | Human alphaherpesvirus 2 | 1 |
Data from ChEMBL 36 via Core Engine