Assay Detail
Functional
CHEMBL5349985
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Antiviral activity against Vaccinia virus Copenhagen infected in human HFF cells assessed as reduction in viral replication measured after 3 days
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Vaccinia virus |
| Cell Type | HFF |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
An Overview of Antivirals against Monkeypox Virus and Other Orthopoxviruses.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 5.17 | 5.48 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1512080 | METHISAZONE | 2.0 | 1 | 5.48 |
| CHEMBL240095 | — | — | 1 | 4.85 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1512080 | METHISAZONE | EC50 | = | 3300.0 | nM | 5.48 |
| CHEMBL240095 | — | EC50 | = | 14000.0 | nM | 4.85 |