Assay Detail
Functional
CHEMBL5349986
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against Cowpox virus Brighton infected in human HFF cells assessed as reduction in viral replication measured after 3 days
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Vaccinia virus |
| Cell Type | HFF |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
An Overview of Antivirals against Monkeypox Virus and Other Orthopoxviruses.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 4.54 | 4.85 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1512080 | METHISAZONE | 2.0 | 1 | 4.85 |
| CHEMBL240095 | — | — | 1 | 4.22 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1512080 | METHISAZONE | EC50 | = | 14000.0 | nM | 4.85 |
| CHEMBL240095 | — | EC50 | = | 60000.0 | nM | 4.22 |