Assay Detail
Functional
CHEMBL5350722
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiproliferative activity against human MOLM-13 cells incubated for 72 hrs by CCK8 assay
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MOLM-13 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Rational Design of RNA Demethylase FTO Inhibitors with Enhanced Antileukemia Drug-Like Properties.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 5.79 | 5.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5421628 | — | — | 1 | 5.82 |
| CHEMBL5406120 | — | — | 1 | 5.82 |
| CHEMBL5436860 | — | — | 1 | 5.82 |
| CHEMBL5419084 | — | — | 1 | 5.82 |
| CHEMBL5396359 | — | — | 1 | 5.82 |
| CHEMBL5416550 | — | — | 1 | 5.82 |
| CHEMBL5410889 | — | — | 1 | 5.77 |
| CHEMBL5421288 | — | — | 1 | 5.66 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5421628 | — | IC50 | = | 1500.0 | nM | 5.82 |
| CHEMBL5406120 | — | IC50 | = | 1500.0 | nM | 5.82 |
| CHEMBL5436860 | — | IC50 | = | 1500.0 | nM | 5.82 |
| CHEMBL5419084 | — | IC50 | = | 1500.0 | nM | 5.82 |
| CHEMBL5396359 | — | IC50 | = | 1500.0 | nM | 5.82 |
| CHEMBL5416550 | — | IC50 | = | 1500.0 | nM | 5.82 |
| CHEMBL5410889 | — | IC50 | = | 1700.0 | nM | 5.77 |
| CHEMBL5421288 | — | IC50 | = | 2200.0 | nM | 5.66 |