Assay Detail
Binding
CHEMBL5350813
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human SLC13A3 in HepG2 cells by measuring citrus uptake
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | HepG2 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Na(+)/dicarboxylate cotransporter 3 (CHEMBL3712947) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Opportunities and Challenges for Inhibitors Targeting Citrate Transport and Metabolism in Drug Discovery.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.80 | 6.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5405434 | — | — | 1 | 6.80 |
| CHEMBL5422462 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5405434 | — | IC50 | = | 160.0 | nM | 6.80 |
| CHEMBL5422462 | — | IC50 | < | 50.0 | nM | - |