Assay Detail
Binding
CHEMBL5353383
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Inhibition of C-terminal his6-tagged human GRK1
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Targeting GRK2 and GRK5 for treating chronic degenerative diseases: Advances and future perspectives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.06 | 4.06 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4090144 | — | — | 1 | 4.06 |
| CHEMBL490 | PAROXETINE | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4090144 | — | IC50 | = | 87000.0 | nM | 4.06 |
| CHEMBL490 | PAROXETINE | IC50 | > | 100000.0 | nM | - |