Assay Detail
Binding
CHEMBL5353390
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Inhibition of GRK1 (unknown origin)
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Targeting GRK2 and GRK5 for treating chronic degenerative diseases: Advances and future perspectives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 4.89 | 4.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL517171 | GSK-1713088A | — | 1 | 4.89 |
| CHEMBL476259 | GSK-1326255A | — | 1 | - |
| CHEMBL4464632 | — | — | 1 | - |
| CHEMBL5398985 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL517171 | GSK-1713088A | IC50 | = | 13000.0 | nM | 4.89 |
| CHEMBL476259 | GSK-1326255A | IC50 | > | 100000.0 | nM | - |
| CHEMBL4464632 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL5398985 | — | IC50 | > | 100000.0 | nM | - |