Assay Detail
Functional
CHEMBL5354458
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against DENV2 New Guinea C infected in golden hamster BHK-21 cells assessed as inhibition of plaque formation and measured after 22 hrs by crystal violet based plaque assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | dengue virus type 2 |
| Cell Type | BHK-21 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Recent two-year advances in anti-dengue small-molecule inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 5.99 | 6.46 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL413376 | SURAMIN HEXASODIUM | 3.0 | 1 | 6.46 |
| CHEMBL1257003 | — | — | 1 | 5.52 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL413376 | SURAMIN HEXASODIUM | EC50 | = | 350.0 | nM | 6.46 |
| CHEMBL1257003 | — | EC50 | = | 3000.0 | nM | 5.52 |