Assay Detail
Binding
CHEMBL5356779
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of c-Met (unknown origin) using Tyr 6 peptide as substrate incubated for 90 mins in presence of ATP by FRET based Z-LYTE kinase assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Targeting MET: Discovery of Small Molecule Inhibitors as Non-Small Cell Lung Cancer Therapy.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.39 | 7.64 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5267265 | — | — | 1 | 7.64 |
| CHEMBL5398102 | — | — | 1 | 7.32 |
| CHEMBL5414728 | — | — | 1 | 7.20 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5267265 | — | IC50 | = | 22.8 | nM | 7.64 |
| CHEMBL5398102 | — | IC50 | = | 47.7 | nM | 7.32 |
| CHEMBL5414728 | — | IC50 | = | 63.0 | nM | 7.20 |