Assay Detail
Functional
CHEMBL5356784
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Antiproliferative activity against human MHCC97H cells assessed as inhibition of cell growth measured after 3 days by CellTiter-Glo assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MHCC97H |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Targeting MET: Discovery of Small Molecule Inhibitors as Non-Small Cell Lung Cancer Therapy.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.75 | 8.06 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5408530 | — | — | 1 | 8.06 |
| CHEMBL5408095 | — | — | 1 | 7.43 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5408530 | — | IC50 | = | 8.8 | nM | 8.06 |
| CHEMBL5408095 | — | IC50 | = | 37.0 | nM | 7.43 |