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Assay Detail

CHEMBL5356794

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Binding
Binding affinity to MET (unknown origin) assessed as inhibition constant
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Hepatocyte growth factor receptor (CHEMBL3717)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Targeting MET: Discovery of Small Molecule Inhibitors as Non-Small Cell Lung Cancer Therapy.
Wang C, Lu X.
J Med Chem (2023) 66 : 7670 -7697
PubMed 37262349 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 8.47 8.47

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL447602 1 8.47

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL447602 Ki = 3.4 nM 8.47