Assay Detail
Binding
CHEMBL5358407
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Inhibition of MPS1 (unknown origin) using MAD1-MAD2 complex as substrate incubated for 1 hr in presence of gamma-[32P]ATP by densitometric analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Development of MPS1 Inhibitors: Recent Advances and Perspectives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 8.40 | 8.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL188343 | REVERSINE | — | 1 | 8.40 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL188343 | REVERSINE | IC50 | = | 4.0 | nM | 8.40 |