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Assay Detail

CHEMBL5358652

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Toxicity
Cytotoxicity against mouse RAW264.7 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Toxicity
Organism Mus musculus
Cell Type RAW264.7
Confidence 1 — Organism
Curated By Autocuration

Target

RAW264.7 (CHEMBL612557)
Type CELL-LINE
Organism Mus musculus

Publication

Research status of indole-modified natural products.
Duan SF, Song L, Guo HY, Deng H, Huang X, Shen QK, Quan ZS, Yin XM.
RSC Med Chem (2023) 14 : 2535 -2563
PubMed 38107170 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 4.54 4.65

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5398627 1 4.65
CHEMBL289191 LUPEOL 1 4.43

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5398627 IC50 = 22600.0 nM 4.65
CHEMBL289191 LUPEOL IC50 = 37300.0 nM 4.43