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Assay Detail

CHEMBL5359055

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Displacement of [3H]CP55940 from human CB2 receptor expressed in Sf9 cell membranes assessed as inhibition constant incubated for 90 mins by by scintillation counter analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Cell Type Sf9
Subcellular Membrane
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Cannabinoid receptor 2 (CHEMBL253)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

A Simple Chiral <sup>1</sup>H NMR Method for the Discrimination of (<i>R</i>)- and (<i>S</i>)-Cannabichromene in Complex Natural Mixtures and Their Effects on TRPA1 Activity.
Dadiotis E, Cui M, Gerasi M, Mitsis V, Melliou E, Makriyannis A, Logothetis DE, Magiatis P.
J Nat Prod (2024) 87 : 77 -84
PubMed 38158562 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 6.58 6.58

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL422704 CANNABICHROMENE 1 6.58

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL422704 CANNABICHROMENE Ki = 260.0 nM 6.58