Assay Detail
Functional
CHEMBL5360003
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antibacterial activity against Salmonella typhimurium ATCC14028 infected in mouse J774.1 cells assessed as reduction in intracellular bacterial growth incubated for 24 hrs in presence of gentamicin by CFU assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Salmonella enterica subsp. enterica serovar Typhimurium |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Target
Salmonella typhimurium (CHEMBL351) ↗| Type | ORGANISM |
| Organism | Salmonella enterica subsp. enterica serovar Typhimurium |
Publication
Discovery of new dibenzodiazepine derivatives as antibacterials against intracellular bacteria.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 6.38 | 6.38 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5408093 | — | — | 1 | 6.38 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5408093 | — | EC50 | = | 420.0 | nM | 6.38 |