Assay Detail
Functional
CHEMBL5360010
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antibacterial activity against ciprofloxacin-resistant Salmonella typhimurium CGC18 infected in mouse RAW264.7 cells assessed as reduction in intracellular bacterial growth incubated for 24 hrs in presence of gentamicin by CFU assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Salmonella enterica subsp. enterica serovar Typhimurium |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Target
Salmonella typhimurium (CHEMBL351) ↗| Type | ORGANISM |
| Organism | Salmonella enterica subsp. enterica serovar Typhimurium |
Publication
Discovery of new dibenzodiazepine derivatives as antibacterials against intracellular bacteria.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 5.90 | 5.90 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5408093 | — | — | 1 | 5.90 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5408093 | — | EC50 | = | 1270.0 | nM | 5.90 |