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Assay Detail

CHEMBL5360494

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to CB2 receptor (unknown origin) assessed as inhibition constant
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Cannabinoid receptor 2 (CHEMBL253)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Synthesis and Evaluation of Natural and Unnatural Tetrahydrocannabiorcol for Its Potential Use in Neuropathologies.
Anand R, Anand LK, Rashid N, Painuli R, Malik F, Singh PP.
J Nat Prod (2024) 87 : 167 -175
PubMed 38355400 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 2 7.32 7.44

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL465 DRONABINOL 4.0 1 7.44
CHEMBL2387541 TETRAHYDROCANNABIVARIN 2.0 1 7.20

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL465 DRONABINOL Ki = 36.4 nM 7.44
CHEMBL2387541 TETRAHYDROCANNABIVARIN Ki = 62.8 nM 7.20