Assay Detail
Binding
CHEMBL5360903
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of mushroom tyrosinase preincubated for 15 mins followed by L-DOPA addition and measured for 15 mins by spectrophotometric assay
4
Total Activities
2
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Agaricus bisporus |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Publication
Biosynthesis of vanillic acid by Ochrobactrum anthropi and its applications.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.25 | 5.25 |
| Inhibition | 2 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL287556 | KOJIC ACID | — | 2 | 5.25 |
| CHEMBL120568 | VANILLIC ACID | — | 2 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL287556 | KOJIC ACID | IC50 | = | 5620.0 | nM | 5.25 |
| CHEMBL120568 | VANILLIC ACID | IC50 | = | 15840000.0 | nM | - |
| CHEMBL120568 | VANILLIC ACID | Inhibition | - | % | - | |
| CHEMBL287556 | KOJIC ACID | Inhibition | - | % | - |