Assay Detail
Functional
CHEMBL5360993
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Agonist activity at KOR receptor in mouse vas deferens assessed as inhibition of electrically evoked vas deferens contraction
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Tissue | Vas deferens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
A systematic review on the kappa opioid receptor and its ligands: New directions for the treatment of pain, anxiety, depression, and drug abuse.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 10.44 | 10.44 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL267495 | NALFURAFINE | 4.0 | 1 | 10.44 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL267495 | NALFURAFINE | IC50 | = | 0.036 | nM | 10.44 |