Assay Detail
Binding
CHEMBL5361027
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Inhibition of Mycobacterium tuberculosis TMPK assessed as inhibition constant by coupled spectrophotometric assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mycobacterium tuberculosis |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Pyrimidine derivatives with antitubercular activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 4.93 | 5.46 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL375569 | — | — | 1 | 5.46 |
| CHEMBL340604 | — | — | 1 | 4.40 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL375569 | — | Ki | = | 3500.0 | nM | 5.46 |
| CHEMBL340604 | — | Ki | = | 40000.0 | nM | 4.40 |