Assay Detail
Binding
CHEMBL5361428
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Inhibition of alpha-glucosidase (unknown origin) using p-nitrophenyl-alpha-D-glucopyranoside as substrate preincubated for 5 mins followed by substrate addition and measured after 5 mins by spectrophotometric analysis
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Synthetic α-glucosidase inhibitors as promising anti-diabetic agents: Recent developments and future challenges.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.39 | 5.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5420199 | — | — | 1 | 5.80 |
| CHEMBL5435862 | — | — | 1 | 5.66 |
| CHEMBL4564900 | — | — | 1 | 5.64 |
| CHEMBL4471826 | — | — | 1 | 5.57 |
| CHEMBL404271 | ACARBOSE | 4.0 | 1 | 4.28 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5420199 | — | IC50 | = | 1600.0 | nM | 5.80 |
| CHEMBL5435862 | — | IC50 | = | 2200.0 | nM | 5.66 |
| CHEMBL4564900 | — | IC50 | = | 2300.0 | nM | 5.64 |
| CHEMBL4471826 | — | IC50 | = | 2700.0 | nM | 5.57 |
| CHEMBL404271 | ACARBOSE | IC50 | = | 53020.0 | nM | 4.28 |