Compound Detail
CHEMBL5420199
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Basic Information
| ChEMBL ID | CHEMBL5420199 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | KUSWNNKZWMZVCC-UHFFFAOYSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
352.8
MW (Da)
3.48
ALogP
2
HBA
2
HBD
62.0
PSA (Ų)
0.74
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 5.8
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Maltase-glucoamylase CHEMBL2074 | IC50 | 5.8 | 5.8 | 1600.0 | 1 |
| Unchecked CHEMBL612545 | IC50 | 5.8 | 5.8 | 1600.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | IC50 | = | 1600.0 | nM | 5.8 | Inhibition of alpha-glucosidase (unknown origin) using p-nitrophenyl-alpha-D-glu... | 36680985 |
| Maltase-glucoamylase | IC50 | = | 1600.0 | nM | 5.8 | Inhibition of intestinal alpha-glucosidase (unknown origin) using p-nitrophenyl-... | 38878516 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 36680985 | 10.1016/j.ejmech.2023.115119 | Unchecked | 1 |
| 38878516 | 10.1016/j.ejmech.2024.116589 | Maltase-glucoamylase | 1 |
Data from ChEMBL 36 via Core Engine