Assay Detail
Binding
CHEMBL5363705
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Inhibition of TBK1 (unknown origin)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Serine/threonine-protein kinase TBK1 (CHEMBL5408) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
The Hitchhiker's Guide to Deep Learning Driven Generative Chemistry.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.49 | 7.65 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5412271 | — | — | 1 | 7.65 |
| CHEMBL3605057 | — | — | 1 | 7.64 |
| CHEMBL5401353 | — | — | 1 | 7.18 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5412271 | — | IC50 | = | 22.4 | nM | 7.65 |
| CHEMBL3605057 | — | IC50 | = | 23.1 | nM | 7.64 |
| CHEMBL5401353 | — | IC50 | = | 66.7 | nM | 7.18 |