Assay Detail
Binding
CHEMBL5364263
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of AspH (unknown origin) by SPE-MS analysis
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Aspartyl/asparaginyl beta-hydroxylase (CHEMBL4680030) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
5-Substituted Pyridine-2,4-dicarboxylate Derivatives Have Potential for Selective Inhibition of Human Jumonji-C Domain-Containing Protein 5.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 6.55 | 7.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5422782 | — | — | 1 | 7.30 |
| CHEMBL5430087 | — | — | 1 | 6.96 |
| CHEMBL5425377 | — | — | 1 | 5.38 |
| CHEMBL5407018 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5422782 | — | IC50 | = | 50.0 | nM | 7.30 |
| CHEMBL5430087 | — | IC50 | = | 110.0 | nM | 6.96 |
| CHEMBL5425377 | — | IC50 | = | 4200.0 | nM | 5.38 |
| CHEMBL5407018 | — | IC50 | > | 50000.0 | nM | - |